Battle of the Toxins!
- Refresh MedSpa
- Apr 13, 2023
- 3 min read

Botox, Xeomin, and Daxxify are all injectable neuromodulators (aka neurotoxins) that are commonly used for cosmetic purposes to reduce the appearance of wrinkles and fine lines. While they are similar in many ways, there are some key differences between these three products that patients should be aware of before deciding which one to use.
Botox
Botox is the most well-known of the three injectables and has been used for cosmetic purposes for over 20 years. Botox is made from botulinum toxin type A and works by blocking nerve signals to the muscles, which reduces the activity of the muscles that cause wrinkles to form. Botox is FDA-approved for the treatment of frown lines, forehead lines, and crow’s feet. It typically takes about two weeks to see the full effects of Botox, and the results can last for up to four months.
Xeomin
Xeomin is another injectable neuromodulator that is made from botulinum toxin type A. Like Botox, Xeomin works by blocking nerve signals to the muscles. However, unlike Botox, Xeomin does not contain any additives, extra protein, or preservatives. This means that patients are less likely to develop an allergic reaction to Xeomin. Also, because it does not have the extra protein, it may last longer than Botox in those that are “Botox-resistant.” Xeomin is FDA-approved for the treatment of frown lines, forehead lines, and crow’s feet. It typically takes about three days to see the full effects of Xeomin, and the results can last for up to three months.
Daxxify
Daxxify is yet another injectable neuromodulator that is made from botulinum toxin type A. It is the latest botulinum toxin to receive FDA approval for lines and wrinkles. However, Daxxify differs from Botox and Xeomin formulations in that it is the only peptide delivered toxin that creates a much stronger bond to the receptors for muscle contraction. This often allows for faster onset and lasting results of up to 6 months and as long as 9 months in some clients. Also, because of the proprietary peptide used in Daxxify, skin quality improvements have been noted by many patients in their studies.
Which one should you choose?
When it comes to choosing between Botox, Xeomin, and Daxxify, it really comes down to personal preference and the advice of your healthcare provider. All three products are safe and effective, when properly administered, and the choice ultimately depends on your individual needs and goals. Some patients may prefer Xeomin because it has fewer additives, while others may prefer Daxxify because it has a faster onset and longer result. Botox remains a popular choice due to its long-standing reputation for safety and efficacy.
It's important to note that while these injectables can help reduce the appearance of wrinkles and fine lines, they are not a permanent solution. Regular maintenance treatments will be needed to maintain the desired results.
In conclusion, while there are some differences between Botox, Xeomin, and Daxxify, they all work by blocking nerve signals to the muscles and are safe and effective treatments for reducing the appearance of wrinkles and fine lines. The choice ultimately comes down to personal preference and the advice of your healthcare provider.
If you are interested in any of the mentioned neuromodulators, please do not hesitate to contact our office. We are here to help and would love the opportunity to help you in your aesthetic journey!
- Refresh MedSpa
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